To: Ted Kaptchu From: Jeffrey Epstein Sent Sun 9/30/2012 3:45:12 PM Subject: Re: Greetings send readings On Sun, Sep 30, 2012 at 11:42 AM, Ted Kaptchuk wrote: Hi Jeffrey, I thought rd check in with you because we done a few things that may be of interest to you. We just published, in Proceeding of the National Academy of Sciences, the first experimental verification that people can have placebo responses without any conscious awareness of any environmental cues. ((Fm attaching.) We think this is an important proof-of-concept that opens many new doors in research. We already have replicated the study with the addition of neuroimaging the subjects and are analyzing the data. We're excited. Also, we have just had the genetic findings I discussed in the spring accepted in PLoS One. (I'm not attaching because it is "quarantined" but if you'd like to see i can send.) While this study is a first step, we're very existed because we were able to get the genetics analyzes from one of the largest randomized controlled trials ever performed and were able to positively replicated this finding. We writing up this data now. Finally, I wanted to tell you that the Pioneer Fund of Robert Wood Johnson Foundation has given us a $250,000 grant towards educating the medical community and health care policy makers concerning placebo effects. As usual, we continue to look for other partners to expand our work in other directions. Thank you for your interest, Best, Ted Ted J. Kaptchuk Associate Professor of Medicine Harvard Medical School Director, Program in Placebo Studies & Therapeutic Encounter Beth Israel Deaconess Medical Center Bosto Phone Email: Web: wvvw.programinplacebostudies.org EFTA_R1_00304905 EFTA01887717