11111111111111111 GENOVA DIAGNOSTICS VIVIVIgdx.net • 800.577.4767 Ordering Physician: The Natural Medicine Clinic Thomas Rotrano, DC 2401 PGA Blvd Ste 132 Palm Beach Gardens. FL 33410 GI Effects f Stool Profiles U.S. ?steal podIng 2000 2200 GI Effects Comprehensive Profile Accession #. A13123t0035 Date Collected: 12/30/2013 Order it: G8310455 Date Received: 12/31/2013 Reference Dated Report: 01/17/2014 Patient: Jeffrey Epstein Date of Birth: 01/20/1953 Telephone: 5616275816 Age: 60 Fax: 5616275895 Sex: Repriled: Male Comment: • IIMIMISO Methodology: DNA Analysis, GCAWS. Microscopic. Colorimetfic. Automated Chemistry. EtA The GI Effects Gastrointestinal Function Profile (2100) and the GI Effects Microbial Ecology Profile (2105) have been replaced by GI Effects Comprehensive Profile (2200) and a new version of the Microbial Ecology Profile (2205), respectively. Updates on the new GI Effects Comprehensive Profile (2200) and Microbial Ecology Profile (2205) include: o The 2200 and 2205 will Include for parasitology, replacing PCR. To enhance clinical utility for our clients, Genova Diagnostics will now offer gold standard technology on its GI Effects Profiles. When multiple stool samples are provided. Genova utilizes a pooled process known as Optimized Parasitology Recovery (OPR). o In order to optimize clinical utility. pathogens (C. difficile, H. pylori, Shiga Toxin E. coll, and Campylobacter app.) will now only be offered as EIA add ons. Clinical utility is best achieved by applying diagnostic assessment for these pathogens within an appropriate clinical differential. o Drug Resistant Genes will be discontinued from reported profiles. Measurement of drug resistant genes indicates presence of DNA for the gene in stool, but does not provide evidence of gene expression. Therefore, no specific treatment indications can be inferred. o PCR will continue to be utilized for assessment of gut microbiota, including predomi