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Sprout Capital Healthcare Technology Portfolios: Since 1995, members of the New Leaf team made all of the healthcare technology investments in the Sprout Funds while they were part of the investing team at the Sprout Group. The Sprout Funds were venture capital funds that were diversified across several sectors including information technology, communications, services, and healthcare technology. The healthcare technology investments in the four Sprout Funds included $1.019 billion in total cost, which was invested in new and follow-on investments in 69 companies from 1995 to 2013. The healthcare technology investments in the first three of these funds are now fully realized, and those in Sprout IX are nearly fully realized. To date, across these four funds, the New Leaf team has generated $1.997 billion of realizations in the aggregate (63 realized investments), and there is $68 million in unrealized value in six unrealized investments. The net annual IRR performance on the healthcare technology portfolios in each of the Sprout Funds would place them in the top quartile of all healthcare venture capital funds tracked by Cambridge Associates in each of the vintage years for which they have established a benchmark". Additionally, over an 18 year period the net annual IRR on these portfolios outperformed relevant public market indices when compared on a public market equivalent basis (PME+)?°, The range of outperformance for each of these portfolios versus the S&P 500, S&P Healthcare, NASDAQ Composite, and the Russell 3000 through March 31, 2014 is the following: Pp Net IRR Outperformance vs. Public Indices (PME+ Methodology) _| | eaticae | Compost | Sino 500 Healthcare Composite 3000 *Healthcare Technology Portfolios '® Please refer to Section III: “Summary of Historical Investment Performance” and Section XHI: “Appendices” and the endnote C in Appendix 4 regarding information provided by Cambridge Associates. 20 Please refer to Section III: “Summary of Historical I

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