13.5 Neural Foundations of Learning 259 in the mean activation of A2 that occurs at time t+epsilon) is on average closest to w x (the amount of energy flowing through the bundle from A1 to A2 at time t). So when Al sends an amount x of energy along the synaptic bundle pointing from Al to A2, then A2’s mean activation is on average incremented/decremented by an amount w x zx. In a similar way, one can define the weight of a bundle of synapses between a certain static or temporal activation-pattern P1 in assembly Al, and another static or temporal activation- pattern P2 in assembly A2. Namely, this may be defined as the number w so that (the amount of energy flowing through the bundle from Ai to A2 at time t)xw best approximates (the probability that P2 is present in A2 at time t+epsilon), when averaged over all times t during which P1 is present in Al. It is not hard to see that Hebbian learning on real synapses between neurons implies Hebbian learning on these virtual synapses between cell assemblies and activation-patterns. These ideas may be developed further to build a connection between neural knowledge rep- resentation and probabilistic logical knowledge representation such as is used in CogPrime’s Probabilistic Logic Networks formalism; this connection will be pursued at the end of Chapter 34, once more relevant background has been presented. 13.5.3 Neural Darwinism A notion quite similar to Hebbian learning between assemblies has been pursued by Nobelist Gerald Edelman in his theory of neuronal group selection, or “Neural Darwinism.” Edelman won a Nobel Prize for his work in immunology, which, like most modern immunology, was based on C. MacFarlane Burnet’s theory of “clonal selection” [Bur62], which states that antibody types in the mammalian immune system evolve by a form of natural selection. From his point of view, it was only natural to transfer the evolutionary idea from one mammalian body system (the immune system) to another (the brain). The sta