From: Jeffrey Epstein <[email protected]> Sent: Monday, February 24, 2014 9:23 PM To: Lesley Groff; Richard Kahn Subject: Re: Joe Thakuria give him 10k =div class=" mail uote">On Mon, Feb 24, 2014 at 5:21 PM, Lesley Groff <mailto > wrote: Sent from my =Phone Begin forwarded message: From: Joseph Thakuria <mailtha Date:=February 24 2014 4:08:44 PM EST To: Lesley Groff gt; Cc: Rich Kahn Subject: Re: Jeffr=y Epstein Really? Ok, done (pending approval through Partners/MGH =RB for my formal research study - about 5 weeks as we discussed). Can we get a little additional software budget for s=condary analyses? At least the $4K worth we would have gotten with an exom=? The rationale for this is so we don't have to completely rely only &=uot;black box" interpretation by Illumina. In my experience, Illumna&=39;s genome interpretation has been historically subpar. Not surprising si=ce they are primarily a next gen DNA sequencing instrumentation company - =ot really focused on analyses and genomic analyses software (though they d= have their own). It may be that we don't pull up a lot of extra info =ith additional software. But we won't know that one way or the other r=lying only on Ilumina's interpretation. Anyway, let me know. The budget/invoice is complete if =e all we are going after is one item: a rapid turnaround whole genome thro=gh Illumina for $11,400. I do think this is the best (highest quality) who=e genome you can get for the money but it is disappointing to me that thei= pricing has been essentially unchanged for years (the reason I expected t=is to be in the $5K range). I do think I can find a whole genome for aroun= $SK (perhaps through CGI) but again I'd question the quality of that =enome. (That was the research rationale for getting 1 from Illumina and 1 =rom CGI to compare results if the funding were available for this). EFTA_R1_01757292 EFTA02581206