Classification: Public Gilead Sciences (Buy, CP: $82.02, TP: $132.00, GILD.OQ, Robyn Karnauskas) 4Q13 update: light taxes create more leverage for Sovaldi 4Q13 product revenues beat consensus by —$250M led by inventory & Sovaldi Sovaldi 4Q13 sales were $139M vs. $75M consensus. Pure demand was roughly $50M in the quarter. Remainder of sales came from inventory stocking & purchase for clinical trials. On the HIV front, mgmt noted that 1Q14 will be weaker with similar trends to 1Q13. This trend is driven by increased purchasing in 4Q13 & being at higher end of inventory range before '14 price increases. '14 guidance for base biz is $11.3-511.5B. We are at 511.56. Reiterate Buy on valuation. We have increased our Sovaldi numbers in '14 by $700M to $5.7B We have taken up our numbers for US & EU Sovaldi over 2014 based on two trends 1) faster than expected launch in EU in a few countries (we previously assumed no sales in 1O in ELI) and 2) strong than expected new script trends in the US. Our new WW quarterly estimates are $1.218, $1.91B, $1.328, and $1.278. In Gilead's early survey work, mgmt has found that the Sovaldi mix roughly reflects real world US genotypic mix (70% GT1 and 30% in GT 2 &3). We calculate every 1K new starts to Sovaldi could add $250M-$300M in revs We assume warehousing in 2Q since we expect Sovaldi interferon free combo in mid 4Q14. We assume monthly new starts declining to —4000lmo avg. in 2Q/3Q from the highs of —13K in 1O. Mgmt color on taxes: supply arrangements allow US sales to have tax benefit Mgmt noted that every $16 of Sovaldi sales led to a lower tax rate of .75-1% irrespective of where the sales are located. Before the call, GILD had noted potential tax benefit over time from greater ex-US sales and IP in Ireland. On call today, we learned of new structuring supply arrangement that allows for US sales to flow out of Ireland manufacturing facility. These benefits will continue over a multi-year period but the magnitud