now THE INTERATIONAL AUTHOR OF SCIENCE . evoiutionar , direct population emergence mutations on..uY pathogenesis th— cli-nrillti- model 0 driver evolution selection -,,,,, treatment prisoner's dilemma . abundance development models human t lymphocyte versus rtitioitm response risk antiretroviral Wm:Ma time replication nrnurt cycles multiple progression C OtOXiC effect adaptive aids denim infection cost lymphocytes variation resistance drug colorectal game spatial gen:'' 'mks interaction biology • ii iiiii, o, , '-dons chromosomal • disease ' ' escape mutation competitioncoo era ion populations together ' . ,I III, II mathematical linear cellular to41ftd cria sisPecies suppressor networks diversity i reciprocity aph fitness virus 1,4,15.0O5 arries 1 virulence repeai,.. . social language i responses - infectil viral strategy instability infectious T-cell tumor public goods PhenotYPe tYPe cancer — ,enetic antigeni5, dilemmas control ' loarl indirect f,.6. au. EVOLUTION THE MATHEMATICS OF EVOLUTION Exploring the equations of life PAGE 50 GOD O COOPERATION 7 April 2015 £50 SUPERHERO GOD DOESN'T REDEFINED PLAY DICE Vol. 50, No. 2612 Why we need each Where cooperation other to succeed meets theology PAGE 50 PAGE 50 5 I 401 6 iii EFTA01203816