From: Faculty of 1000 To: [email protected]> Subject: Optogenetics uncover memory storage, and the best articles of the month. Date: Wed, 11 Jul 2012 15:58:28 +0000 ,,ADVERTISEMENT Having trouble? View in your browser. ;,F1000 Monthly Update Email Header JULY 2012 F1000's 10.000 experts recommend the best articles in the life sciences. 1,374 evaluations were added in the last month, and you can see them all here. IG Best of the Best Some of the articles that caught the attention of our Faculty this month. How fearful memories are stored Convincing evidence for the discrete encoding of memories in ensembles of neurons in the hippocampus. Tumor evolution — implications for therapy Sheds much light on tumor heterogeneity and provides tantalizing evidence of convergent evolution in tumors. Don't just sit there Prolonged sitting is a risk factor for all- cause mortality, independent of physical activity. liw Countering drug side effects Chemical similarity metrics can help in uncovering adverse drug reactions in the early phases of drug development. Second-line HIV treatment success in resource-limited countries Encouraging results for proposed second-line therapy of HIV-infected patients in resource-limited settings. Gut microbiota: a special relationship This paper extends our understanding of intestinal microbe-host interactions by [;,,F1000 Reports Open-access journals publishing reports, written by Faculty Members, on hot topics with reference to the evaluated literature. Biology Reports The future of genomics in pathology Recent technical advances in pathology bring us closer to using whole genomic data to rapidly diagnose diseases like cancer and to effectively tailor treatment programs to the individual. F1000 Report by Dennis P. Wall and Peter J. Tonellato (Medicine Reports Crosstalk between metabolic and neuropsychiatric disorders Converging evidence indicates that insulin receptors in the CNS may unde