FOUNDATION MEDICINE, INC. One Kendall Square Cambridge, MA 02139 December 28, 2012 Gates Ventures, LLC 2365 Carillon Point Kirkland WA 98033 Phone: Attn: General Counsel Re: Management Rights Ladies and Gentlemen: This letter shall confirm our agreement that, effective as of the date hereof, Foundation Medicine, Inc. (the "Company") hereby grants Gates Ventures, LLC (the "Investor") the following contractual information rights, in addition to any information rights provided to the Investor pursuant to that certain Amended and Restated Investors' Rights Agreement, dated as September 10, 2012, by and among the Company, the Investor and certain other investors (as it may be amended and/or restated from time to time, the "Investors' Rights Agreement"), in connection with, and in partial consideration of, the Investor's purchase of shares of the Company's Series B Preferred Stock, par value $0.0001 per share (the "Series B Preferred Stock"), on the date hereof. I. The Investor shall have the right to one telephone conference with the Company's Chief Executive Officer (the "CEO") (or other senior officer of the Company approved in writing by the Investor) during each quarter of each fiscal year of the Company. Such telephone conference (i) shall include a reasonably comprehensive quarterly retrospective and prospective review of the Company's business, (ii) shall last for a mutually agreed-upon duration as necessary to provide for such review and (iii) shall occur at a mutually agreed-upon time. At each meeting, the CEO (or such other approved senior officer) shall deliver to the Investor (a) information concerning the Company which the Investor may reasonably request, and (b) such other information concerning the matters discussed at each meeting of the Company's Board of Directors (the "Board") that has occurred since the Investor's last meeting pursuant to sections (1) or (2) of this letter agreement, including, without limitation, all w