CONFIDENTIAL July , 2013 William H. Gates [Provide Appropriate Address] RE: Letter of Agreement Regarding Foundation Medicine, Inc. Dear Bill: This letter sets forth the agreement, effective as of the date set forth above (the "Effective Date"), by and between you, William H. Gates ("Mr. Gates"), and me, Boris Nikolic ("Mr. Nikolic"), in order to settle and resolve our respective rights and obligations in connection with our prior agreement relating my receiving between 30% and 40% of the future profits of a $30 Million to $50 Million investment fund intended to be created and funded by Mr. Gates, but which was never launched (the "Prior Agreement"). In order to settle and resolve our respective rights and obligations under the Prior Agreement, the Owner and Mr. Nikolic have agreed as follows: New Investment SE-251912 vl Mr. Gates, through an affiliate, beneficially owned and controlled by Mr. Gates (a "Purchasing Affiliate", and together with Mr. Gates, hereinafter referred to as the "Owner"), purchased an interest (the "Interest") in Foundation Medicine, Inc., a Delaware corporation with principal offices located in Cambridge, Massachussetts ("Foundation Medicine"), at a price of $ (the "Purchase Price"). If at any time or from time to time hereafter, the Owner (which, for purposes of this Agreement, shall also include any other Purchasing Affiliate beneficially owned and controlled by Mr. Gates that purchases an interest in Foundation Medicine) shall, in its sole and absolute discretion, make additional investments in Foundation Medicine, the Owner shall give prompt written notice to Mr. Nikolic of such additional investments, and the Interest shall be deemed to include all such additional investments, and the Purchase Price shall be increased by the amount of the purchase price paid by the Owner for all such additional investments. The term "Interest" shall also include any and all dividends, payments, distributions, proceeds, o