Blending Humanitarian Care With Scientific Investigation POI Preventive Oncology International May 12, 2015 RE: Cervical Cancer Screening Program Sponsorship Jeffrey Epstein USVI Dear Mr Epstein, This request for funding is respectfully submitted to your foundation's interest in early diagnosis. Preventive Oncology International, a 501(c)(3) Public Charity, was founded in 1997 to blend humanitarian work with good clinical science. The foundation, known as P01, is based in the United States, and has worked with international collaborators in the Dominican Republic, Mexico, Peru, and rural China. P01's first objective was to define the effectiveness of the technologies that existed; and then improve screening for cervical cancer, a disease that affects 530,000 women worldwide and causes 270,000 deaths annually. We began by working on molecular testing for human papillomavirus (HPV), the virus that is known to cause virtually all cervical cancers. To date, more than 60,000 women have participated in our clinical trials, leading to improved care for millions worldwide. Our trials for cervical cancer screening have been documented in 100+ peer-reviewed scientific publications. See https://archive.org/details/BelinsoniPubMed22015 . Discoveries include significant breakthroughs in screening technologies and the creation of a functional and streamlined community- based method for reaching underserved populations in rural communities. Our full list of accomplishments in cervical cancer prevention is noteworthy: 1. P01 introduced Human Papilloma Virus (HPV) testing to China a. The results of our studies led to CSFDA approval of HPV testing assays in China. 2. P01 introduced Liquid-based cytology for cervical cancer screening to China a. The results led to SFDA approval of Liquid-based cytology tests in China, as an alternative to the dry slide-based method of the Pap smear 3. P01 accumulated international data that was provided as evidence for HPV test