From: Jay Lombard To: "Jeffrey E." <jeevacationggmail.com> Subject: Re: j epstein Date: Sat, 16 Jun 2018 13:50:04 +0000 Not to overwhelm you, so last article... J Investig Allergol Clin Immunol. 2013;23(3):212. Nonhistaminergic idiopathic angioedema may be a presentation of mast cell activation syndrome. Akin LB. Comment on Nonhistaminergic idiopathic angioedema: clinical response to icatibant. [J Investig Allergol Clin Immunol. 2012] On Sat, Jun 16, 2018 at 9:42 AM Jay Lombard J Nippon Med Sch. 2002 Aug;69(4):347-54. - wrote: Morphological and histochemical characteristics of mast cells and the content of in-tissue histamine in various pathological parathyroids: do mast cells participate in hormone secretion in human parathyroids? Iwamura Ti Shimizu K Tanaka S. Author information Abstract The possibility of the participation of mast cells in human parathyroid hormone secretion was studied with regard to the frequency, distribution, and sub-types of mast cells and the content of in-tissue histamine, a chemical mediator in mast-cell granules, in human parathyroids with various pathological conditions. The above factors were compared between those of a 'normal' parathyroid group and those of 'pathological' parathyroids associated with adenoma and hyperplasia. Specimens were scanned for the mean value of the mast cellnumber per field of microscopic view and for the ratio of the mast cell number in glandular parenchymal tissue to that in interstitial tissue. The activated state of the mast cells was examined through classifying the mast cells into two sub-types, mucosal mast cells and connective-tissue mast cells. The high-performance liquid chromatography (HPLC) method was used for assay of in-tissue histamine. The frequency of mast cells showed no difference between the groups, whereas the EFTA00990058