From: Nathan Wolfe To: Jeffrey Epstein <[email protected]> Subject: Prep Notes for Monday Call Date: Fri, 12 Apr 2013 20:44:00 +0000 Hey Jeffrey Great to hang out with you and nice to meet Steve. Here are prep notes on kicking off the Microbial Hypersexuality study: There are a few solid ways to start: 1) cross-sectional human studies; 2) wild rodent studies; or 3) lab studies with known models (eg rabies, toxo). Each have benefits, but I'd propose we start with option 1 and add to two human studies we're already funded to do in Cameroon and DR Congo (study abstracts below). Basically we'll add a hypersexuality index questionnaire, increase sample size, modify specimens types (eg add genital swabs), and add lab studies to give us a link between hypersexuality and microbial diversity. The studies will be the first of their kind and generate loads of results related to hypersexuality, novel STI discovery and associations between sexuality and microbial diversity that we can follow-up on. Geographic location is ideal (high and understudied viral diversity) and we already have protocols, plans, and funding in place to leverage. My team put together details (statement of work, budget, one pager etc) which I can forward if you like, and now does seem to be the ideal window to latch on to these studies. We can review and figure out specifics when we talk Monday... For now have an entertaining weekend wherever you are and don't do anything I wouldn't do! Nathan HIV Prevention for Populations at Risk in Cameroon (Female Sex Workers & Men who have sex with Men), funded by USAID Sex work and same sex practices are illegal in Cameroon, however, the HIV prevalence among female SW has been reported as 37% and 35% among MSM. The study is taking place in 7 cities in 7 provinces of Cameroon (Yaounde, Douala, Bertoua, Ngaoundere, Bafoussam, Bamenda and Kribi) where quantitative interviews will be conducted with up to 150 female sex workers (FSW) per city