From: Misha Gromov To: "jeffrey E." <jeevacation®gmail.com> Subject: Re: Date: Sun, 15 May 2016 08:25:07 +0000 50/50 is generous; also will make me more involved if you take it. the erson I s oke to is below is the (rather long) summary/advertisement she sent me on my request We plan to bring to the healthcare market what we call a HealthSpan Pass — an individual recommendation (an individually designed healthcare pathway) on molecular adjustments for healthy ageing and healthspan extension, based on simultaneous analysis of near all molecules (comprising a human metabolome) in a microsample of blood by metabolomics approach being imposed on our academic expertise in molecular metabolism of ageing. In the production workflow we utilise blood metabolomics technology for identification of the molecular changes associated with ageing and biomarkers of age-related disorders. Current and past medicinal interventions, individual lifestyle habits and dietary preferences are also reflected in a molecular composition of blood as a universal metabolic information integrator. From such analysis imposed on our know-why on human molecular metabolism, we are able to determine the impact of particular metabolites on the developmental trajectory of healthy ageing, to diagnose pre-pathological healthspan violations and to indicate the precise molecular targets for personalised fine tuning of ageing metabolism. Additionally, to expand availability of our service and to make it distance- independent, we plan to develop a self-sampling device compatible with our technological metabolomics platform, and to bring it to a medical self-care market as a valuable side product. In the developmental process of our main product HealthSpan Pass, two more add-value side products will be created: UniMetaMarker (universal metabolic biomarker panel) and AgeMetaMarker (healthspan metabolic biomarker panel). A biomarker panel is a set of molecules, selected from human metabolome, w