From: Lesley Groff To: Joseph Thakuria Subject: Re: Jeffrey Epstein-Coordinate Payment Date: Wed, 04 Dec 2013 16:16:09 +0000 terrific Joe...I am so very thankful for people like you who can dedicate themselves to this sort of research...wishing you all the best and we will watch for your next email with invoice... Lesley On Dec 3, 2013, at 4:48 PM, Joseph Thakuria wrote: It's exciting since with the exception of the clinical whole genome (that Illumina has offered for years but at a very low volume due to cost and very limited clinical indication (for now)), the other stuff (including the clinical exomes) hasn't really even been around beyond a year or so. The iPS cell lines would have been something you could only get from a handful of labs worldwide and, even then, the researchers would most likely be prioritizing their own projects - not doing "one-off" individualized cell lines for interested parties. Anyway, I'll make sure he gets access to the latest and greatest and he can choose those things that are of the greatest scientific and personal interest for him from the list. Maybe along the way also help some of these kids with genetic disorders that we haven't been able to molecularly diagnose through conventional Sanger sequencing at MGH. Cheers, Joe On Tue, Dec 3, 2013 at 4:36 PM, Lesley Groff > wrote: thanks so much for this Joe...we will await an invoice...and I'm sure Jeffrey will get back to you on all of this. Lesley On Dec 3, 2013, at 4:24 PM, Joseph Thakuria wrote: Hi Lesley (and Jeffrey), I was hoping to have a draft invoice ready today for Jeffrey's review but can I get another 24-48hrs to work on this? I'm going to put together costs for: a) whole genome sequencing through illumina b) bioinformatic support for JE's wgs data c) iPS cell line (ie, adult stem cell) generation from the pro bono fibroblast cultures I made from his skin biopsy +1- if he's interested further differentiation of these iPS cell lines to iPS-deriv